tc-peptide  (GenScript corporation)

Journal: International Journal of Molecular Sciences

Article Title: Advances in Chitosan-Based Nanoparticles for Drug Delivery

doi: 10.3390/ijms22179652

Figure Lengend Snippet: Current application examples of chitosan nanoparticles and nanocomposites in drug delivery.

Article Snippet: SPION NPs encapsulated with TAT peptide/TC and TMC , Electrostatic interaction , siRNA Targeted anti-cancer therapy , Cytotoxicity, cellular internalization, in vivo pharmacokinetic and biodistribution, colony formation assay, wound healing assay, Chick chorioallantoic membrane (CAM) assay , [ ] .

Techniques: In Vitro, In Vivo, Activity Assay, Drug discovery, α-Glucosidase Inhibition Assay, Apoptosis Assay, Solvent, Evaporation, Dissolution, Dispersion, Antioxidant Activity Assay, Gene Expression, Ex Vivo, Vaccines, Permeability, Adjuvant, Emulsification, MTT Assay, Emulsion, Membrane, Adsorption, Virus, Diffusion-based Assay, Hemolysis Assay, Cytotoxicity Assay, Injection, Double Emulsion, Inhibition, Formulation, Isolation, Derivative Assay, Luciferase, Plasmid Preparation, Transfection, Colony Assay, Wound Healing Assay, Chick Chorioallantoic Membrane Assay, Clonogenic Assay, Transwell Migration Assay

Journal: International Journal of Molecular Sciences

Article Title: Advances in Chitosan-Based Nanoparticles for Drug Delivery

doi: 10.3390/ijms22179652

Figure Lengend Snippet: CAM assay of HIF-1α/CD73 siRNA loaded TAT-TMC/TC/SPION nanocarriers suppressed in vivo tumor development and angiogenesis . Reproduced with permission from Elsevier (Copyright©2020).

Article Snippet: SPION NPs encapsulated with TAT peptide/TC and TMC , Electrostatic interaction , siRNA Targeted anti-cancer therapy , Cytotoxicity, cellular internalization, in vivo pharmacokinetic and biodistribution, colony formation assay, wound healing assay, Chick chorioallantoic membrane (CAM) assay , [ ] .

Techniques: Chick Chorioallantoic Membrane Assay, In Vivo

Journal: Molecular imaging

Article Title: Imaging the Met Receptor Tyrosine Kinase (Met) and Assessing Tumor Responses to a Met Tyrosine Kinase Inhibitor in Human Xenograft Mouse Models with a [ 99m Tc] (AH-113018) or Cy 5 ⋆⋆ (AH-112543) Labeled Peptide

doi:

Figure Lengend Snippet: Biodistribution of [ 99m Tc]-Met Peptide in MKN-45 Xenografts after 30, 60, 120, and 180 Minutes

Article Snippet: Radiosynthesis of [ 99m Tc]-Met Peptide (AH-113018) [ 99m Tc]-Met peptide was synthesized using [ 99m Tc]O 4 − (Cardinal Health, Dublin, OH) and a chelate kit labeling method.

Techniques:

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Article Title: The role of radionuclide probes for monitoring anti-tumor drugs efficacy: A brief review

doi: 10.1016/j.biopha.2017.08.079

Figure Lengend Snippet: Optical and SPECT imaging of [111In]DTPAHQA in (a) control and (b) chemotherapy-treated MCF-7 tumor-bearing mice. Chemotherapy group received a single i.p. injection of cyclophosphamide (265 mg/kg) followed by i.v. injection of [111In] DTPA-HQA 72 h later. Images were acquired 24 h after probe injection. Reproduced with permission from [52].

Article Snippet: Zhang et al. [ 57 ] evaluated SPECT imaging of 99m Tc-peptide-Z HER2:342 , an affibody molecule with high affinity for HER2, for monitoring the therapeutic response to trastuzumab in nude mice bearing HER2-positive SKOV-3 xenografts.

Techniques: Single Photon Emission Computed Tomography, Imaging, Control, Injection

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Article Title: The role of radionuclide probes for monitoring anti-tumor drugs efficacy: A brief review

doi: 10.1016/j.biopha.2017.08.079

Figure Lengend Snippet: Representative Dual SPECT/CT images of EL4 lymphoma apoptosis with 111In-labeled annexin A5-CCPM in A) non-treated mouse and E) treated mouse. Representative fluorescence molecular tomographic images of B) non-treated mouse and F) treated mouse. Representative autoradiographs of excised tumors of C) non-treated group and G) treated group. Fluorescence images of the same slides used in autoradiographic studies in D) non-treated group and H) treated group. This research was originally published in JNM. R. Zhang, W. Lu, X. Wen, M. Huang, M. Zhou, D. Liang, C. Li, “Annexin A5-Conjugated Polymeric Micelles for Dual SPECT and Optical Detection of Apoptosis” J. Nucl. Med. 52 (2011) 958–964. The Society of Nuclear Medicine and Molecular Imaging, Inc © [80].

Article Snippet: Zhang et al. [ 57 ] evaluated SPECT imaging of 99m Tc-peptide-Z HER2:342 , an affibody molecule with high affinity for HER2, for monitoring the therapeutic response to trastuzumab in nude mice bearing HER2-positive SKOV-3 xenografts.

Techniques: Single Photon Emission Computed Tomography, Labeling, Fluorescence, Imaging